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The appetite-related effects that patients notice first are driven by rapid central nervous system signaling, while the substantial changes in body composition, glycemic markers and cardiovascular risk reflect cumulative metabolic adaptation that requires sustained exposure

PMID: 34439468

Neuroendocrine normalization: Studies in aged animal models document normalized anterior pituitary function and restored luteinizing hormone and follicle-stimulating hormone pulsatility following administration

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Dihexa drives synaptogenesis via HGF/c-Met